ATS – Acoustic Liquid Dispenser

Open platform for application flexibilityLowest starting & dead volumes1.0 nl minimum drop sizeUniversal liquid calibration for simplicityConfidence in your liquid dispensingLasting precision and performanceLow cost of ownershipQuiet operation

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What is True Non-contact Technology?


A means for transferring liquid from a source to a destination without the use of pins, tips, syringes or a capillary device. The transfer is direct, accurate, and extremely repeatable.

The ATS Acoustic Liquid Dispenser transfers chemical and
biological solutions with unparalleled accuracy and precision directly from one plate to another. The ATS is flexible, application friendly and is highly adaptable to meet a broad range of liquid handling needs and requirements. Using EDC Biosystems’ patented acoustic transfer process, you can perform your experiments with the lowest starting and dead volumes of any liquid handling device on the market. There are no print heads with fixed-spacing or volume-specific tip sizes to deal with, and no cross-contamination. The ATS easily integrates with other laboratory equipment for a complete automated solution.

Small footprint, rapid installation, & setup, wide variety of plates, 1,0nl dispence, low deadvolume, low maintenance, easy to use!

Higher Performance: The ATS can dispense from 96, 384, 1536 & 3456 wellplates. Transfer liquid from your choice of source plate into any destination substrate imaginable.

Total liquid transfer volumes start as low as 1.0 nL. A wide range of liquids can be transferred by the ATS using any calibration available on the system.

The ATS has a lower starting and dead volume than any other automated instrument, delivering high performance while conserving resources and reducing costs.

  • Pre-plating of compounds for screening
  • Dose-responses hit-picking
  • Pate reformatting and consolidation
  • PCR
  • Protein crystallography
  • Niche arrays

And  the delivery of liquids onto microfluidic devices,

The ATS is designed and built ready to handle any application requiring accurate and precise liquid transfers of ultra-low volumes.

2nl droplet dispenseDispensed 2 nl droplet landing onto a destination positioned upside-down and directly above the source well. Regardless of high velocity at impact and orientation, the droplet does not disintegrate or fall due to the dominating effect of the liquid surface tension at this volume scale.

General Specifications

  • Fluid viscosity: 0-20 cP
  • Surface tension: 27-72 dynes/cm
  • Density: 0.5-2.0 g/cm3
  • Transfer volume: 1 nl to 2 μl+* * Larger volumes increase transfer times

System components

  • Internal coupling fluid circulation system
  • Wellplate charge-neutralizing system
  • CCD camera wellplate monitoring system
  • Wellplate interference safety sensor

Special features

  • Application and mapping software included
  • Quick-change destination grippers
  • Real-time data management system
  • Single-position plate load/unloading available

Dimensions and Facilities

  • Size:  71 cm W x 78 cm D x 65 cm H
  • Weight: 115 kg
  • Clean dry air: 60-80 psi, 2 CFM
  • Transfer variability: <10% CV
  • 384 wellplate replication: <2.5 min*
  • 1536 wellplate replication: <6 min*
  • 3456 wellplate replication: <13 min*
  • Electrical: 110 VAC, 50/60 Hz or 230 VAC, 50 Hz
  • Coupling fluid: distilled water (400 ml)
  • Internal barcode reader
  • Internal destination plate flipper
  • Ethernet-based connectivity
  • Built-in Windows based PC
  • Landscape wellplate orientation for both source and destination plates
  • Workcell integration and automation-ready


* For a single unit volume well to well transfer

disp examp

fluorescence data graf







The ATS utilizes real-time sensing and focus technology. Immediately before every dispense. A sensing pulse gathers information on the present acoustic path. Upon receiving a return signal (Step #1),the acoustic lens makes necessary adjustments (Step #2) and then fires the dispensing pulse (Step #3). This entire process takes less than 50 milliseconds. A key benefit of the ATS real-time dispensing process is its ability to reveal potential problems in the acoustic path. Errors are logged and the ATS moves onto the next dispense. Missed wells are identified and can be re-tried or excluded from the final analyses. This greatly reduces the incidence of false-negatives in experiments.


Wagner is proud to be the european partner for the ATS